La oxigenoterapia hiperbárica complementaria favorece una curación satisfactoria en pacientes con enfermedad de Crohn refractaria
- Autores:Marley Ribeiro Feitosa, Omar Féres Filho, Camila Mussolin Tamaki, Camila Perazzoli, Mário Vinícius Angelete Alvarez Bernardes, Rogério Serafim Parra, José Joaquim Ribeiro da Rocha, Omar Féres
- Fecha de publicación:March 19, 2016
- Tipo:Articulos
Abstract
PURPOSE: To investigate de adjunctive effect of Hyperbaric Oxygen Therapy in a group of patients with refractory Crohn’s disease.
METHODS: A total of 29 subjects with refractory Crohn’s disease were submitted to daily sessions of Hyperbaric Oxygen Therapy, in a 2800 Sechrist Monoplace Hyperbaric Chamber (Sechrist, USA) pressurized to 2.4 ATA. Each session lasted 2 hours. The endpoint was closure of enterocutaneous fistulas and complete healing of Pyoderma Gangrenosum and perineal Crohn’s disease.
RESULTS: A total of 829 HBOT sessions were performed and no complications were noted. Overall success rate was 76% (22 cases). Pyoderma Gangrenosum and enterocutaneous fistulas had the highest successful healing rates (100% and 91%, respectively). Perineal Crohn’s disease healing rate was 65%.
CONCLUSION: Adjunctive Hyperbaric Oxygen Therapy promoted satisfactory healing in a group of patients with refractory Crohn’s disease.